Technical aspects of amyloid imaging for Alzheimer's disease
1 Medical Research Council Clinical Sciences Centre and Division of Neuroscience, Imperial College London, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
2 Wolfson Molecular Imaging Centre, University of Manchester, 27 Palatine Road, Withington, Manchester M20 3LJ, UK
Alzheimer's Research & Therapy 2011, 3:25 doi:10.1186/alzrt87Published: 31 August 2011
[11C]Pittsburgh Compound B positron emission tomography has now been extensively used to evaluate the amyloid load in different types of dementia and has become a powerful research tool in the field of neurodegenerative diseases. In the present short review we discuss the properties of amyloid imaging agent [11C]Pittsburgh Compound B, the different modalities of molecular imaging, image processing and data analysis, and newer amyloid imaging agents.